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IMPRS / Graduate Schools

Science Slam

12.05.2016, 7 p.m.

with iGEM Team Bonn
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caesar seminar series

03.05.2016, 11 a.m.

Prof. Dr. Christof Niehrs, Institute of Molecular Biology, Mainz
"Not so canonical Wnt signaling during sperm maturation"

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04.05.2016, 11 am

Dr. Valery Grinevich
German Cancer Research Center (DKFZ) and University of Heidelberg
"Central oxytocin pathway in the brain - from fear to sociality"

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11.05.2016, 3 pm

Adam R. Kampff
Sainsbury Wellcome Centre, London
"Cortex + CMOS: Distributed, whole-brain, single-unit electrical recordings"

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Caesar is a Neuroscience research institute of the Max Planck Society. Caesar’s research is interdisciplinary with scientists from various research areas working together on the topics of cellular signal processing and the neural foundations of behavior. 


Biosensor measures signaling molecules within cilia - Scientists can measure the dynamics of signaling molecules in subcellular compartments

The novel biosensor within the flagellum of mouse sperm. Above, an image of a single mouse sperm acquired with a light microscope is shown. Within this image, the flagellum is marked red. The middle image displays a normal and the lower image an increased cAMP concentration along the flagellum. Whereby blue corresponds to a low and red to a high cAMP concentration. A comparison of the two images demonstrates: cAMP concentration changes differ significantly in different areas of the flagellum.

Bonn, 22.03.2016. Scientists of the Research Center caesar in Bonn, an Institute of the Max Planck Society, developed a new biosensor, which allows to measure nanomolar levels of the second messenger cAMP.  The sensor makes it possible to study cAMP signaling with high precision, even in subcellular compartments. Using this new biosensor, the scientists of the Minerva Max Planck Research Group “Molecular Physiology“ headed by Dagmar Wachten and of the Department “Molecular Sensory Systems” headed by Benjamin Kaupp revealed how the production of cAMP is regulated in the flagella of sperm cells from mice. [more]