Li, Q., Centola, M., Keppner, D., Valero Moreno, J., and Famulok, M. (2023).Reconfigurable Nanopolygons Made of DNA Catenanes. Bioconjugate Chem 34, 105-110. 
Schmitz, A., Weber, A., Mehtap, B., Breuers, S., Fieberg, V., Famulok, M., and Mayer, G. (2021). A SARS-CoV-2 spike binding DNA aptamer that inhibits pseudovirus infection in vitro by an RBD independent mechanism. Angew Chem Int Ed Engl 60, 10279-10285.
Valero, J. and Famulok, M. (2020). Regeneration of burnt bridges on a DNA catenane walker. Angew Chem Int Ed 59, 16366-16370.
Ma, Y., Centola, M., Keppner, D., and Famulok, M.
(2020).
Interlocked DNA nanojoints for reversible thermal sensing. Angew Chem
Int Ed 59, 12455-12459.
Hornung, T., O’Neill, H.A., Logie, S.C., Fowler, K.M.,
Duncan, J.E., Rosenow, M., Bondre, A.S., Tinder, T., Maher, V., Zarkovic, J.,
Zhong, Z., Richards, M.N., Wei, X., Miglarese, M.R., Mayer, G., Famulok, M., and Spetzler, D. (2020).
ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes. Nucleic Acids Res 48, 4013-4027.
Viegas, A., Yin, D.M., Borggraefe, J., Viennet, T.,
Falke, M., Schmitz, A., Famulok, M., and Etzkorn, M. (2020).
Molecular architecture of a network of potential intracellular EGFR modulators: ARNO, CaM, phospholipids, and the juxtamembrane segment. Structure 28, 54-62.
Å kugor, M., Valero, J., Murayama, K., Centola, M., Asanuma, H., and Famulok, M. (2019). Orthogonally photocontrolled non-autonomous DNA walker. Angew Chem Int Ed 58, 6948-6951.
Tonapi, S.S., Pannu, V., Duncan, J.E., Rosenow, M., Helmstetter, A., Magee, D., Zhang, Q., Tinder, T.T., Richards, M., Halbert D.D., Famulok, M., Spetzler, D., Miglarese, M.R., O'Neill, H.A., and Mayer, G. (2019). Translocation of a cell surface spliceosomal complex induces alternative splicing events and lymphoma cell necrosis. Cell Chem Biol 26, 756-764.
Haydell, M.W., Centola, M., Adam, V., Valero, J., and Famulok M. (2018). Temporal and Reversible Control of a DNAzyme by Orthogonal Photoswitching. J Am Chem Soc 140, 16868-16872.
Kerzhner M., Matsuoka H., Wuebben C., Famulok M., and Schiemann O. (2018). High yield spin labeling of long RNAs for EPR spectroscopy. Biochemistry 57, 2923-2931.
Valero J., Pal N., Dhakal S., Walter N.G., and Famulok M. (2018). A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks. Nat Nanotechnol 13, 496-503.
Domenyuk V., Gatalica Z., Santhanam R., Wei X., Stark A., Kennedy P., Toussaint B., Levenberg S., Wang J., Xiao N., Greil R., Rinnerthaler G., Gampenrieder S.P., Heimberger A.B., Berry D.A., Barker A., Quackenbush J., Marshall J.L., Poste G., Vacirca J.L., Vidal G.A., Schwartzberg L.S., Halbert D.D., Voss A., Magee D., Miglarese M.R., Famulok M., Mayer G., and Spetzler D. (2018). Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes. Nat Commun 9, 1219.
Adam V., Prusty D.K., Centola M., Škugor M., Hannam J.S., Valero J., Klöckner B., and Famulok M. (2018). Expanding the toolbox of photoswitches for DNA nanotechnology using arylazopyrazoles. Chemistry 24, 1062-1066.
Prusty D.K., Adam V., Zadegan R.M., Irsen S, and Famulok M. (2018). Supramolecular aptamer nano-constructs for receptor-mediated targeting and light triggered release of chemotherapeutics into cancer cells. Nat Commun 9, 535.
Yin, D.M., Hammler, D., Peter, M.F., Marx, A., Schmitz, A., and Hagelueken, G. (2018). Inhibitor-directed spin labelling - a high precision and minimally invasive technique to study the conformation of proteins in solution. Chem Eur J 24, 6665 - 6671.
Domenyuk, V., Zhong, Z., Stark, A., Xiao, N., O'Neill, H.A., Wei, X., Wang, J., Tinder, T.T., Tonapi, S., Duncan, J., Hornung, T., Hunter, A., Miglarese, M.R., Schorr, J., Halbert, D.D., Quackenbusch, J., Poste, G., Berry, D.A., Mayer, G., Famulok, M., and Spetzler, D. (2017). Plasma exosome profiling of cancer patients by a next generation systems biology approach. Sci Rep 7, 42741.
Valero, J., Lohmann, F., Keppner, D., and Famulok, M. (2016). Single-stranded tile stoppers for interlocked DNA architectures. ChemBioChem 17, 1146-1149.
Weigandt, J., Chung, C.-L., Jester, S. S., and Famulok, M. (2016). Daisy chain rotaxanes made from interlocked DNA nanostructures. Angew Chem Int Ed Engl 55, 5512-5516.
Lentz, C.S., Sattler, J.M., Fendler, M., Gottwalt, S., Halls, V.S., Strassel, S., Arriens, S., Hannam, J.S., Specht, S., Famulok, M., Mueller, A.-K., Hoerauf, A., and Pfarr, K. (2015). In vitro activity of wALADin benzimidazoles against different life cycle stages of plasmodium parasites. Antimicrob Agents Chemother 59, 654 - 658.
Lu, C.-H., Cecconello, A., Oi, X.-J., Wu, N., Jester, S.-S., Famulok, M., Matthies, M., Schmidt, T.-L., and Willner, I. (2015). Switchable reconfiguration of a seven-ring interlocked DNA catenane nanostructure. Nano Lett 15, 7133 – 7137.
Zhai, J., Zhang, L., Mojsilovic-Petrovic, J., Jian, X., Thomas, J., Homma, K., Schmitz, A., Famulok, M., Ichijo, H., Randazzo, P. A., and Kalb, R.G. (2015). Inhibition of cytohesins protects against genetic models of motor neuron disease. J Neurosci 35, 9088 - 9105.
Famulok, M. and Mayer, G. (2014). Aptamers and SELEX in chemistry & biology. Chem Biol 21, 1055 - 1058.
Jester, S.S. and Famulok, M. (2014). Mechanically interlocked DNA nanostructures for functional devices. Acc Chem Res 47, 1700 - 1709.
Lentz, C.S., Halls, V.S., Hannam, J.S., Strassel, S., Lawrence, S.H., Jaffe, E.K., Famulok, M., Hoerauf, A., and Pfarr, K.M. (2014). wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem 57, 2498 - 2510.
Li, T., Lohmann, F. and Famulok, M. (2014). Interlocked DNA nanostructures controlled by a reversible logic circuit. Nat Commun 5, 4940.
Lohmann, F., Valero, J., and Famulok, M. (2014). A novel family of structurally stable double stranded DNA catenanes. Chem Commun (Camb) 50, 6091 - 6093.
Lohmann, F., Weigandt, J., Valero, J., and Famulok, M. (2014). Logic gating by macrocycle displacement using a double-stranded DNA 3 rotaxane shuttle. Angew Chem Int Ed Engl 53, 10372 - 10376.
Lu, C.H., Qi, X.J., Cecconello, A., Jester, S.S., Famulok, M., and Willner, I. (2014). Switchable reconfiguration of an interlocked DNA olympiadane nanostructure. Angew Chem Int Ed Engl 53, 7499 - 7503.
Ackermann, D. and Famulok, M. (2013). Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology. Nucleic Acids Res 41, 4729 - 4739.
Hussein, M., Bettio, M., Schmitz, A., Hannam, J.S., Theis, J., Mayer, G., Dosa, S., Gütschow, M., and Famulok, M. (2013). Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin. Angew Chem Int Ed Engl 52, 9529 - 9533.
Lentz, C.S., Halls, V., Hannam, J.S., Niebel, B., Strübing, U., Mayer, G., Hoerauf, A., Famulok, M., and Pfarr, K.M. (2013) A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem Biol 20, 177 - 187.
Lentz, C.S., Stumpfe, D., Bajorath, J., Famulok, M., Hoerauf, A., and Pfarr, K. M (2015). New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria. Bioorg Med Chem Lett 23, 5558 - 5562.
Li, T. and Famulok, M. (2013). I-motif-programmed functionalization of DNA nanocircles. J Am Chem Soc 135, 1593 - 1599.
Niebel, B., Wosnitza, C.I., and Famulok, M. (2013). RNA-aptamers that modulate the RhoGEF activity of Tiam1. Bioorg Med Chem 21, 6239 - 6246.
Ackermann, D., Jester, S.S., and Famulok, M. (2012). Design strategy for DNA rotaxanes with a mechanically reinforced PX100 axle. Angew Chem Int Ed Engl 51, 6771 - 6775
Albertoni, B., Hannam, J.S., Ackermann, D., Schmitz, A., and Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chem Commun (Camb) 48, 1272 - 1274.
Bill, A., Schmitz, A., König, K., Heukamp, L.C., Hannam, J. S., and Famulok, M. (2012). Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells. Plos One 7, e41179.
Hons, M., Niebel, B., Karnowski, N., Weiche, B., and Famulok, M. (2012). Pan-selective aptamers for the family of small GTPases. Chembiochem 13, 1433-1437.
Li, J., Malaby, A.W., Famulok, M., Sabe, H., Lambright, D.G., and Hsu, V.W. (2012). Grp1 plays a key role in linking insulin signaling to glut4 recycling. Dev Cell 22, 1286-1298.
Li, T., Ackermann, D., Hall, A.M., and Famulok, M. (2012). Input-dependent induction of oligonucleotide structural motifs for performing molecular logic. J Am Chem Soc 134, 3508-3516.
Lohmann, F., Ackermann, D., and Famulok, M. (2012). Reversible light switch for macrocycle mobility in a DNA rotaxane. J Am Chem Soc 134, 11884-11887.
Miao, B., Skidan, I., Yang, J., You, Z., Fu, X., Famulok, M., Schaffhausen, B., Torchilin, V., Yuan, J., and Degterev, A. (2012). Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene 31, 4317 - 4332.
Rohrbach, F., Karadeniz, H., Erdem, A., Famulok, M., and Mayer, G. (2012). Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes. Anal biochem 421, 454 - 459.
Vinkenborg, J.L., Mayer, G., and Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angew Chem Int Ed Engl 51, 9176-9180.
Beyer, M., Thabet, Y., Müller, R.U., Sadlon, T., Classen, S., Lahl, K., Basu, S., Zhou, X., Bailey-Bucktrout, S.L., Krebs, W., Schönfeld, E.A., Böttcher, J., Golovina, T., Mayer, C.T., Hofmann, A., Sommer, D., Debey-Pascher, S., Endl, E., Limmer, A., Hippen, K.L., Blazar, B.R., Balderas, R., Quast, T., Waha, A., Mayer, G., Famulok, M., Knolle, P.A., Wickenhauser, C., Kolanus, W., Schermer, B., Bluestone, J.A., Barry, S.C., Sparwasser, T., Riley, J.L., and Schultze, J.L. (2011). Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 12, 898-907.
Bill, A., Blockus, H., Stumpfe, D., Bajorath, J., Schmitz, A., and Famulok, M. (2011). A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time. J Am Chem Soc 133, 8372 - 8379.
Famulok, M., and Mayer, G. (2011). Aptamer modules as sensors and detectors. Acc Chem Res 44, 1349-1358.
Niebel, B., Weiche, B., Mueller, A.L., Li, D.Y., Karnowski, N., and Famulok, M. (2011). A luminescent oxygen channeling biosensor that measures small GTPase activation. Chem Commun 47, 7521-7523.
Vinkenborg, J.L., Karnowski, N., and Famulok, M. (2011). Aptamers for allosteric regulation. Nat Chem Biol 7, 519-527.
Ackermann, D., Rasched, G., Verma, S., Schmidt, T.L., Heckel, A., and Famulok, M. (2010). Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chem Commun (Camb) 46, 4154-4156.
Ackermann, D., Schmidt, T.L., Hannam, J.S., Purohit, C.S., Heckel, A., and Famulok, M. (2010). A double-stranded DNA rotaxane. Nat Nanotechn 5, 436-442.
Lünse, C.E., Michlewski, G., Hopp, C.S., Rentmeister, A., Caceres, J.F., Famulok, M., and Mayer, G. (2010). An aptamer targeting the apical-loop domain modulates pri-miRNA processing. Angew Chem Int Ed Engl 49, 4674-4677.
Mayer, G., Ahmed, M.S., Dolf, A., Endl, E., Knolle, P.A., and Famulok, M. (2010). Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures. Nat Protoc 5, 1993-2004.
Niebel, B., Lentz, C., Pofahl, M., Mayer, G., Hoerauf, A., Pfarr, K.M., and Famulok, M. (2010). ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling. Chemistry 16, 11100-11107.
Stumpfe, D., Bill, A., Novak, N., Loch, G., Blockus, H., Geppert, H., Becker, T., Schmitz, A., Hoch, M., Kolanus, W., Famulok, M., and Bajorath, J. (2010). Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions. ACS Chem Biol 5, 839-849.
Klotz, L., Burgdorf, S., Dani, I., Saijo, K., Flossdorf, J., Hucke, S., Alferink, J., Nowak, N., Beyer, M., Mayer, G., Langhans, B., Klockgether, T., Waisman, A., Eberl, G., Schultze, J., Famulok, M., Kolanus, W., Glass, C., Kurts, C., and Knolle, P.A. (2009). The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med 206, 2079-2089.
Jones, C.A., Nishiya, N., London, N.R., Zhu, W., Sorensen, L.K., Chan, A., Lim, C.J., Chen, H., Zhang, Q., Schultz, P.G., Hayallah, A.M., Thomas, R.K., Famulok, M., Zhang, K., Ginsberg, H.H., and Li, D.Y. (2009). Slit2-Robo4 signaling promotes vascular stability by blocking Arf6 activity. Nat Cell Biol 11, 1325-1331.
Gronewold, T.M., Baumgartner, A., Hierer, J., Sierra, S., Blind, M., Schäfer, F., Blümer, J., Tillmann, T., Kiwitz, A., Kaiser, R., Zabe-Kühn, M., Quandt, E., and Famulok, M. (2009). Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS). J Proteome Res 8, 3568-3577.
Beyer, M., Karbach, J., Mallmann, M.R., Zander, T., Eggle, D., Classen, S., Debey-Pascher, S., Famulok, M., Jäger, E., and Schultze, J.L. (2009). Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with division arrest anergy. Cancer Res 69, 4346-4354.
Erdem, A., Karadeniz, H., Mayer, G., Famulok, M., and Caliskan, A. (2009). Electrochemical sensing of aptamer-protein interactions using magnetic particle assay and single-use sensor technology. Electroanalysis 21, 1278-1284.
Famulok, M. (2009). Exploring chemical space with aptamers. J Med Chem 52, 6951-6957.
Bi, X., Schmitz, A., Hayallah, A.M., Song, J.N., and Famulok, M. (2008). Affinity-based labeling of cytohesins with a bifunctional SecinH3 photoaffinity probe. Angew Chem Int Ed 47, 9565-9568.
Fusz, S., Srivatsan, S.G., Ackermann, D., and Famulok, M. (2008). Photocleavable initiator nucleotide substrates for an aldolase ribozyme. J Org Chem 73, 5069-5077.
Hafner, M., Vianini, E., Albertoni, B., Marchetti, L., Grüne, I., Gloeckner, C., and Famulok, M. (2008). Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization. Nat Prot 3, 579-587.
Heckel, A., and Famulok, M. (2008). Building objects from nucleic acids for a nanometer world. Biochimie 90, 1096-1107.
Mayer, G., Ackermann, D., Kuhn, N., and Famulok, M. (2008). Construction of DNA architectures with RNA hairpins. Angew Chem Int Ed 47, 971-973.
Raddatz, M.S., Dolf, A., Endl, E., Knolle, P., Famulok, M., and Mayer, G. (2008). Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting. Angew Chem Int Ed 47, 5190-5193.
Rasched, G., Ackermann, D., Schmidt, T.L., Broekmann, P., Heckel, A., and Famulok, M. (2008). DNA minicircles with gaps for versatile functionalization. Angew Chem Int Ed 47, 967-970.
Rentmeister, A., Mayer, G., Kuhn, N., and Famulok, M. (2008). Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides. Biol Chem 389, 127-134.
Schmitz, A., Weber, A., Mehtap, B., Breuers, S., Fieberg, V., Famulok, M., and Mayer, G. (2021). A SARS-CoV-2 spike binding DNA aptamer that inhibits pseudovirus infection in vitro by an RBD independent mechanism. Angew Chem Int Ed Engl 60, 10279-10285.
Valero, J. and Famulok, M. (2020). Regeneration of burnt bridges on a DNA catenane walker. Angew Chem Int Ed 59, 16366-16370.
Ma, Y., Centola, M., Keppner, D., and Famulok, M.
(2020).
Interlocked DNA nanojoints for reversible thermal sensing. Angew Chem
Int Ed 59, 12455-12459.
Hornung, T., O’Neill, H.A., Logie, S.C., Fowler, K.M.,
Duncan, J.E., Rosenow, M., Bondre, A.S., Tinder, T., Maher, V., Zarkovic, J.,
Zhong, Z., Richards, M.N., Wei, X., Miglarese, M.R., Mayer, G., Famulok, M., and Spetzler, D. (2020).
ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes. Nucleic Acids Res 48, 4013-4027.
Viegas, A., Yin, D.M., Borggraefe, J., Viennet, T.,
Falke, M., Schmitz, A., Famulok, M., and Etzkorn, M. (2020).
Molecular architecture of a network of potential intracellular EGFR modulators: ARNO, CaM, phospholipids, and the juxtamembrane segment. Structure 28, 54-62 e5.
Å kugor, M., Valero, J., Murayama, K., Centola, M., Asanuma, H., and Famulok, M. (2019). Orthogonally photocontrolled non-autonomous DNA walker. Angew Chem Int Ed 58, 6948-6951.
Tonapi, S.S., Pannu, V., Duncan, J.E., Rosenow, M., Helmstetter, A., Magee, D., Zhang, Q., Tinder, T.T., Richards, M., Halbert D.D., Famulok, M., Spetzler, D., Miglarese, M.R., O'Neill, H.A., and Mayer, G. (2019). Translocation of a cell surface spliceosomal complex induces alternative splicing events and lymphoma cell necrosis. Cell Chem Biol 26, 756-764.e6.
Haydell, M.W., Centola, M., Adam, V., Valero, J., and Famulok M. (2018). Temporal and Reversible Control of a DNAzyme by Orthogonal Photoswitching. J Am Chem Soc 140, 16868-16872.
Kerzhner M., Matsuoka H., Wuebben C., Famulok M., and Schiemann O. (2018). High yield spin labeling of long RNAs for EPR spectroscopy. Biochemistry 57, 2923-2931.
Valero J., Pal N., Dhakal S., Walter N.G., and Famulok M. (2018). A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks. Nat Nanotechnol 13, 496-503.
Domenyuk V., Gatalica Z., Santhanam R., Wei X., Stark A., Kennedy P., Toussaint B., Levenberg S., Wang J., Xiao N., Greil R., Rinnerthaler G., Gampenrieder S.P., Heimberger A.B., Berry D.A., Barker A., Quackenbush J., Marshall J.L., Poste G., Vacirca J.L., Vidal G.A., Schwartzberg L.S., Halbert D.D., Voss A., Magee D., Miglarese M.R., Famulok M., Mayer G., and Spetzler D. (2018). Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes. Nat Commun 9, 1219.
Adam V., Prusty D.K., Centola M., Škugor M., Hannam J.S., Valero J., Klöckner B., and Famulok M. (2018). Expanding the toolbox of photoswitches for DNA nanotechnology using arylazopyrazoles. Chemistry 24, 1062-1066.
Prusty D.K., Adam V., Zadegan R.M., Irsen S, and Famulok M. (2018). Supramolecular aptamer nano-constructs for receptor-mediated targeting and light triggered release of chemotherapeutics into cancer cells. Nat Commun 9, 535.
Yin, D.M., Hammler, D., Peter, M.F., Marx, A., Schmitz, A., and Hagelueken, G. (2018). Inhibitor-directed spin labelling - a high precision and minimally invasive technique to study the conformation of proteins in solution. Chem Eur J 24, 6665 - 6671.
Domenyuk, V., Zhong, Z., Stark, A., Xiao, N., O'Neill, H.A., Wei, X., Wang, J., Tinder, T.T., Tonapi, S., Duncan, J., Hornung, T., Hunter, A., Miglarese, M.R., Schorr, J., Halbert, D.D., Quackenbusch, J., Poste, G., Berry, D.A., Mayer, G., Famulok, M., and Spetzler, D. (2017). Plasma exosome profiling of cancer patients by a next generation systems biology approach. Sci. Rep. 7, 42741.
Valero, J., Lohmann, F., Keppner, D., and Famulok, M. (2016). Single-stranded tile stoppers for interlocked DNA architectures. ChemBioChem 17, 1146-1149.
Weigandt, J., Chung, C.-L., Jester, S. S., and Famulok, M. (2016). Daisy chain rotaxanes made from interlocked DNA nanostructures. Angew. Chem. Int. Ed. Engl. 55, 5512-5516.
Lentz, C.S., Sattler, J.M., Fendler, M., Gottwalt, S., Halls, V.S., Strassel, S., Arriens, S., Hannam, J.S., Specht, S., Famulok, M., Mueller, A.-K., Hoerauf, A., and Pfarr, K. (2015). In vitro activity of wALADin benzimidazoles against different life cycle stages of plasmodium parasites. Antimicrob. Agents Chemother.59, 654 - 658.
Lu, C.-H., Cecconello, A., Oi, X.-J., Wu, N., Jester, S.-S., Famulok, M., Matthies, M., Schmidt, T.-L., and Willner, I. (2015). Switchable reconfiguration of a seven-ring interlocked DNA catenane nanostructure. Nano Lett. 15, 7133 – 7137.
Zhai, J., Zhang, L., Mojsilovic-Petrovic, J., Jian, X., Thomas, J., Homma, K., Schmitz, A., Famulok, M., Ichijo, H., Randazzo, P. A., and Kalb, R.G. (2015). Inhibition of cytohesins protects against genetic models of motor neuron disease. J. Neurosci. 35, 9088 - 9105.
Famulok, M. and Mayer, G. (2014). Aptamers and SELEX in chemistry & biology. Chem. Biol. 21, 1055 - 1058.
Jester, S.S. and Famulok, M. (2014). Mechanically interlocked DNA nanostructures for functional devices. Acc. Chem. Res. 47, 1700 - 1709.
Lentz, C.S., Halls, V.S., Hannam, J.S., Strassel, S., Lawrence, S.H., Jaffe, E.K., Famulok, M., Hoerauf, A., and Pfarr, K.M. (2014). wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J. Med. Chem. 57, 2498 - 2510.
Li, T., Lohmann, F. and Famulok, M. (2014). Interlocked DNA nanostructures controlled by a reversible logic circuit. Nat. Commun. 5, 4940.
Lohmann, F., Valero, J., and Famulok, M. (2014). A novel family of structurally stable double stranded DNA catenanes. Chem. Commun. (Camb.) 50, 6091 - 6093.
Lohmann, F., Weigandt, J., Valero, J., and Famulok, M. (2014). Logic gating by macrocycle displacement using a double-stranded DNA 3 rotaxane shuttle. Angew. Chem. Int. Ed. Engl. 53, 10372 - 10376.
Lu, C.H., Qi, X.J., Cecconello, A., Jester, S.S., Famulok, M., and Willner, I. (2014). Switchable reconfiguration of an interlocked DNA olympiadane nanostructure. Angew. Chem. Int. Ed. Engl. 53, 7499 - 7503.
Ackermann, D. and Famulok, M. (2013). Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology. Nucleic Acids Res. 41, 4729 - 4739.
Hussein, M., Bettio, M., Schmitz, A., Hannam, J.S., Theis, J., Mayer, G., Dosa, S., Gütschow, M., and Famulok, M. (2013). Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin. Angew. Chem. Int. Ed. Engl. 52, 9529 - 9533.
Lentz, C.S., Halls, V., Hannam, J.S., Niebel, B., Strübing, U., Mayer, G., Hoerauf, A., Famulok, M. & Pfarr, K.M. (2013) A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem. Biol. 20, 177 - 187.
Lentz, C.S., Stumpfe, D., Bajorath, J., Famulok, M., Hoerauf, A., and Pfarr, K. M (2015). New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria. Bioorg. Med. Chem. Lett. 23, 5558 - 5562.
Li, T. and Famulok, M. (2013). I-motif-programmed functionalization of DNA nanocircles. J. Am. Chem. Soc. 135, 1593 - 1599.
Niebel, B., Wosnitza, C.I., and Famulok, M. (2013). RNA-aptamers that modulate the RhoGEF activity of Tiam1. Bioorg. Med. Chem. 21, 6239 - 6246.
Ackermann, D., Jester, S.S., and Famulok, M. (2012). Design strategy for DNA rotaxanes with a mechanically reinforced PX100 axle. Angew. Chem. In.t Ed. Engl. 51, 6771 - 6775
Albertoni, B., Hannam, J.S., Ackermann, D., Schmitz, A., and Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chem. Commun. (Camb.) 48, 1272 - 1274.
Bill, A., Schmitz, A., König, K., Heukamp, L.C., Hannam, J. S., and Famulok, M. (2012). Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells. Plos One 7, e41179.
Hons, M., Niebel, B., Karnowski, N., Weiche, B., and Famulok, M. (2012). Pan-selective aptamers for the family of small GTPases. Chembiochem 13, 1433 - 1437.
Li, J., Malaby, A.W., Famulok, M., Sabe, H., Lambright, D.G., and Hsu, V.W. (2012). Grp1 plays a key role in linking insulin signaling to glut4 recycling. Dev. Cell 22, 1286 - 1298.
Li, T., Ackermann, D., Hall, A.M., and Famulok, M. (2012). Input-dependent induction of oligonucleotide structural motifs for performing molecular logic. J. Am. Chem. Soc. 134, 3508 - 3516.
Lohmann, F., Ackermann, D., and Famulok, M. (2012). Reversible light switch for macrocycle mobility in a DNA rotaxane. J. Am. Chem. Soc. 134, 11884 - 11887.
Miao, B., Skidan, I., Yang, J., You, Z., Fu, X., Famulok, M., Schaffhausen, B., Torchilin, V., Yuan, J., and Degterev, A. (2012). Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene 31, 4317 - 4332.
Rohrbach, F., Karadeniz, H., Erdem, A., Famulok, M., and Mayer, G. (2012). Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes. Analytical biochemistry 421, 454 - 459.
Vinkenborg, J.L., Mayer, G. & Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angew. Chem. In.t Ed. Engl. 51, 9176 - 9180.
Beyer, M., Thabet, Y., Müller, R.U., Sadlon, T., Classen, S., Lahl, K., Basu, S., Zhou, X., Bailey-Bucktrout, S.L., Krebs, W., Schönfeld, E.A., Böttcher, J., Golovina, T., Mayer, C.T., Hofmann, A., Sommer, D., Debey-Pascher, S., Endl, E., Limmer, A., Hippen, K.L., Blazar, B.R., Balderas, R., Quast, T., Waha, A., Mayer, G., Famulok, M., Knolle, P.A., Wickenhauser, C., Kolanus, W., Schermer, B., Bluestone, J.A., Barry, S.C., Sparwasser, T., Riley, J.L., and Schultze, J.L. (2011). Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat. Immunol. 12, 898 - 907.
Bill, A., Blockus, H., Stumpfe, D., Bajorath, J., Schmitz, A. & Famulok, M. (2011) "A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time" J. Am. Chem. Soc. 133, 8372 - 8379
Famulok, M. & Mayer, G. (2011) "Aptamer modules as sensors and detectors" Acc. Chem. Res. 44, 1349 - 1358
Niebel, B., Weiche, B., Mueller, A.L., Li, D.Y., Karnowski, N. & Famulok, M. (2011) "A luminescent oxygen channeling biosensor that measures small GTPase activation" Chem. Commun. 47, 7521 - 7523
Vinkenborg, J.L., Karnowski, N. & Famulok, M. (2011) "Aptamers for allosteric regulation" Nat. Chem. Biol. 7, 519 - 527
Ackermann, D., Rasched, G., Verma, S., Schmidt, T.L., Heckel, A. & Famulok, M. (2010) "Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates" Chem. Commun. (Camb.) 46, 4154 - 4156
Ackermann, D., Schmidt, T.L., Hannam, J.S., Purohit, C.S., Heckel, A. & Famulok, M. (2010) "A double-stranded DNA rotaxane" Nat. Nanotechn. 5, 436 - 442
Lünse, C.E., Michlewski, G., Hopp, C.S., Rentmeister, A., Caceres, J.F., Famulok, M. & Mayer, G. (2010) "An aptamer targeting the apical-loop domain modulates pri-miRNA processing" Angew. Chem. Int. Ed. Engl. 49, 4674 - 4677
Mayer, G., Ahmed, M.S., Dolf, A., Endl, E., Knolle, P.A. & Famulok, M. (2010) "Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures" Nat. Protoc. 5, 1993 - 2004
Niebel, B., Lentz, C., Pofahl, M., Mayer, G., Hoerauf, A., Pfarr, K.M. & Famulok, M. (2010) "ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling" Chemistry 16, 11100 - 11107
Stumpfe, D., Bill, A., Novak, N., Loch, G., Blockus, H., Geppert, H., Becker, T., Schmitz, A., Hoch, M., Kolanus, W., Famulok, M. & Bajorath, J. (2010) "Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions" ACS Chem. Biol. 5, 839 - 849
Klotz, L., Burgdorf, S., Dani, I., Saijo, K., Flossdorf, J., Hucke, S., Alferink, J., Nowak, N., Beyer, M., Mayer, G., Langhans, B., Klockgether, T., Waisman, A., Eberl, G., Schultze, J., Famulok, M., Kolanus, W., Glass, C., Kurts, C. & Knolle, P.A. (2009) "The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity" J. Exp. Med. 206, 2079-2089
Jones, C.A., Nishiya, N., London, N.R., Zhu, W., Sorensen, L.K., Chan, A., Lim, C.J., Chen, H., Zhang, Q., Schultz, P.G., Hayallah, A.M., Thomas, R.K., Famulok, M., Zhang, K., Ginsberg, H.H. & Li, D.Y. (2009) "Slit2-Robo4 signaling promotes vascular stability by blocking Arf6 activity" Nat. Cell Biol. 11, 1325-1331
Gronewold, T.M., Baumgartner, A., Hierer, J., Sierra, S., Blind, M., Schäfer, F., Blümer, J., Tillmann, T., Kiwitz, A., Kaiser, R., Zabe-Kühn, M., Quandt, E. & Famulok, M. (2009) "Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS)" J. Proteome Res. 8, 3568-3577
Beyer, M., Karbach, J., Mallmann, M.R., Zander, T., Eggle, D., Classen, S., Debey-Pascher, S., Famulok, M., Jäger, E. & Schultze, J.L. (2009) "Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy" Cancer Res. 69, 4346-4354
Erdem, A., Karadeniz, H., Mayer, G., Famulok, M. & Caliskan, A. (2009) "Electrochemical sensing of aptamer-protein interactions using magnetic particle assay and single-use sensor technology" Electroanalysis 21, 1278-1284
Famulok, M. (2009) "Exploring chemical space with aptamers" J. Med. Chem. 52, 6951-6957
Bi, X., Schmitz, A., Hayallah, A.M., Song, J.N. & Famulok, M. (2008) "Affinity-based labeling of cytohesins with a bifunctional SecinH3 photoaffinity probe" Angew. Chem. Int. Ed. 47, 9565-9568
Fusz, S., Srivatsan, S.G., Ackermann, D. & Famulok, M. (2008) "Photocleavable initiator nucleotide substrates for an aldolase ribozyme" J. Org. chem. 73, 5069-5077
Hafner, M., Vianini, E., Albertoni, B., Marchetti, L., Grüne, I., Gloeckner, C. & Famulok, M. (2008) "Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization" Nat. Prot. 3, 579-587
Heckel, A. & Famulok, M. (2008) "Building objects from nucleic acids for a nanometer world" Biochimie 90, 1096-1107
Mayer, G., Ackermann, D., Kuhn, N. & Famulok, M. (2008) "Construction of DNA architectures with RNA hairpins" Angew. Chem. Int. Ed. 47, 971-973
Raddatz, M.S., Dolf, A., Endl, E., Knolle, P., Famulok, M. & Mayer, G. (2008) "Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting" Angew. Chem. Int. Ed. 47, 5190-5193
Rasched, G., Ackermann, D., Schmidt, T.L., Broekmann, P., Heckel, A. & Famulok, M. (2008) "DNA minicircles with gaps for versatile functionalization" Angew. Chem. Int. Ed. 47, 967-970
Rentmeister, A., Mayer, G., Kuhn, N. & Famulok, M. (2008) "Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides" Biol. Chem. 389, 127-134