It is our pleasure to invite you to a seminar entitled ”Physiological basis of noise-induced hearing loss in a tympanal ear” by Dr. Georgina Fenton, Warren Lab, Department of Neuroscience, Psychology and Behaviour, University of Leicester on Wednesday, October 30th at 11 am, media room.
Acoustic overexposure, such as listening to music too loud and too often, results in noise-induced hearing loss. The pathologies of this prevalent sensory disorder begin in the synapses of the primary auditory receptors, their postsynaptic partners and supporting cells. Ears of all animals have specialised ciliated sound-sensitive receptor cells that transduce sound into electrical potentials. In vertebrates, auditory transduction potentials are generated in non-spiking hair cells and converted into spikes in postsynaptic neurons that travel to the central nervous system to give the percept of sound. In insects, transduction and spike-generation take place within the same auditory neuron. Despite this difference in architecture across the animal kingdom, they all suffer from excessive influx of positive ions when acoustically overstimulated and, as such, possibly disrupting their ability to encode sound. Here, we used the physiologically-accessible locust ear to measure in vivo electrophysiological and morphological changes in the auditory neurons directly after noise exposure.