Publications

2020

Han, Z., Lo, W.S., Lightfoot, J.W., Witte, H., Sun, S., and Sommer, R.J. (2020). Improving transgenesis efficiency and CRISPR-associated tools through codon optimization and native intron addition in Pristionchus nematodes. Genetics 216, 947-956.

Sieriebriennikov, B., Sun, S., Lightfoot, J.W., Witte, H., Moreno, E., Roedelsperger, C., and Sommer, R.J. (2020). Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell. PLoS Genet 16, e1008687.

Akduman, N., Lightfoot, J.W., Roeseler, W., Witte, H., Lo, W.-S., Roedelsperger, C., and Sommer, R.J. (2020). Bacterial vitamin B-12 production enhances nematode predatory behavior. ISME J 14, 1494-1507.

2019

Moreno, E., Lightfoot, J.W., Lenuzzi, M., and Sommer, R.J. (2019). Cilia drive developmental plasticity and are essential for efficient prey detection in predatory nematodes. Proc Biol Sci 286, 20191089.

Lightfoot, J.W., Wilecki, M., Roedelsperger, C., Moreno, E., Susoy, V., Witte, H., and Sommer, R.J. (2019). Small peptide-mediated self-recognition prevents cannibalism in predatory nematodes. Science 364, 86-89.

2017

Moreno, E., Sieriebriennikov, B., Witte, H., Rodelsperger, C., Lightfoot, J.W., and Sommer, R.J. (2017). Regulation of hyperoxia-induced social behaviour in Pristionchus pacificus nematodes requires a novel cilia-mediated environmental input. Sci Rep 7, 17550.

2016

Lightfoot, J.W., Wilecki, M., Okumura, M., and Sommer, R.J. (2016). Assaying Predatory Feeding Behaviors in Pristionchus and Other Nematodes. J Vis Exp, e54404.

Lightfoot, J.W., Chauhan, V.M., Aylott, J.W., and Rodelsperger, C. (2016). Comparative transcriptomics of the nematode gut identifies global shifts in feeding mode and pathogen susceptibility. BMC Res Notes 9, 142.

Kulkarni, A., Lightfoot, J.W., and Streit, A. (2016). Germline organization in Strongyloides nematodes reveals alternative differentiation and regulation mechanisms. Chromosoma 125, 725-745.

Gao, J., Barroso, C., Zhang, P., Kim, H.-M., Li, S., Labrador, L., Lightfoot, J., Gerashchenko, M.V., Labunskyy, V.M., Dong, M.-Q., et al. (2016). N-terminal acetylation promotes synaptonemal complex assembly in C. elegans. Genes Dev 30, 2404-2416.

2015

Wilecki, M., Lightfoot, J.W., Susoy, V., and Sommer, R.J. (2015). Predatory feeding behaviour in Pristionchus nematodes is dependent on phenotypic plasticity and induced by serotonin. J Exp Biol 218, 1306-1313.

2014

Silva, N., Ferrandiz, N., Barroso, C., Tognetti, S., Lightfoot, J., Telecan, O., Encheva, V., Faull, P., Hanni, S., Furger, A., et al. (2014). The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression. Dev Cell 31, 503-511.

2013

Labrador, L., Barroso, C., Lightfoot, J., Mueller-Reichert, T., Flibotte, S., Taylor, J., Moerman, D.G., Villeneuve, A.M., and Martinez-Perez, E. (2013). Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis. PLoS Genet 9, e1003497.

2011

Lightfoot, J., Testori, S., Barroso, C., and Martinez-Perez, E. (2011). Loading of meiotic cohesin by SCC-2 is required for early processing of DSBs and for the DNA damage checkpoint. Curr Biol 21, 1421-1430.

2008

Martinez-Perez, E., Schvarzstein, M., Barroso, C., Lightfoot, J., Dernburg, A.F., and Villeneuve, A.M. (2008). Crossovers trigger a remodeling of meiotic chromosome axis composition that is linked to two-step loss of sister chromatid cohesion. Genes Dev 22, 2886-2901.

2007

Jackson, R.J., Elvers, K.T., Lee, L.J., Gidley, M.D., Wainwright, L.M., Lightfoot, J., Park, S.F., and Poole, R.K. (2007). Oxygen reactivity of both respiratory oxidases in Campylobacter jejuni: the cydAB genes encode a cyanide-resistant, low-affinity oxidase that is not of the cytochrome bd type. J Bacteriol 189, 1604-1615.