Valero, J., and Famulok, M. (2020). Regeneration of Burnt Bridges on a DNA Catenane Walker. Angew Chem Int Ed 59, 16366-16370.
Ma, Y., Centola, M., Keppner, D., and Famulok, M.
(2020).
Interlocked DNA Nanojoints for Reversible Thermal Sensing. Angew Chem
Int Ed 59, 12455-12459.
Hornung, T., O’Neill, H.A., Logie, S.C., Fowler, K.M.,
Duncan, J.E., Rosenow, M., Bondre, A.S., Tinder, T., Maher, V., Zarkovic, J.,
Zhong, Z., Richards, M.N., Wei, X., Miglarese, M.R., Mayer, G., Famulok, M., and Spetzler, D. (2020).
ADAPT Identifies an ESCRT Complex Composition That Discriminates VCaP From LNCaP Prostate Cancer Cell Exosomes. Nucleic Acids Res 48, 4013-4027.
Viegas, A., Yin, D.M., Borggraefe, J., Viennet, T.,
Falke, M., Schmitz, A., Famulok, M., and Etzkorn, M. (2020).
Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment. Structure 28, 54-62 e5.
Škugor M., Valero J., Murayama K., Centola M., Asanuma H., Famulok M. (2019). Orthogonally Photocontrolled Non-Autonomous DNA Walker Angew Chem Int Ed 58, 6948-6951.
Tonapi, S.S., Pannu, V., Duncan J.E., Rosenow M., Helmstetter A., Magee D., Zhang Q., Tinder T.T., Richards M., Halbert D.D., Famulok M., Spetzler D., Miglarese M.R., O'Neill H.A., Mayer G. (2019). Translocation of a Cell Surface Spliceosomal Complex Induces Alternative Splicing Events and Lymphoma Cell Necrosis Cell Chem Biol 26, 756-764.e6.
Haydell M.W., Centola M., Adam V., Valero J., Famulok M. (2018). Temporal and Reversible Control of a DNAzyme by Orthogonal Photoswitching. J Am Chem Soc 140, 16868-16872.
Kerzhner M., Matsuoka H., Wuebben C., Famulok M., Schiemann O. (2018). High yield spin labeling of long RNAs for EPR spectroscopy. Biochemistry 57, 2923-2931.
Valero J., Pal N., Dhakal S., Walter N.G., Famulok M. (2018). A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks. Nat Nanotechnol 13, 496-503.
Domenyuk V., Gatalica Z., Santhanam R., Wei X., Stark A., Kennedy P., Toussaint B., Levenberg S., Wang J., Xiao N., Greil R., Rinnerthaler G., Gampenrieder S.P., Heimberger A.B., Berry D.A., Barker A., Quackenbush J., Marshall J.L., Poste G., Vacirca J.L., Vidal G.A., Schwartzberg L.S., Halbert D.D., Voss A., Magee D., Miglarese M.R., Famulok M., Mayer G., Spetzler D. (2018). Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes. Nat Commun 9, 1219.
Adam V., Prusty D.K., Centola M., Škugor M., Hannam J.S., Valero J., Klöckner B., Famulok M. (2018). Expanding the Toolbox of Photoswitches for DNA Nanotechnology Using Arylazopyrazoles. Chemistry 24, 1062-1066.
Prusty D.K., Adam V., Zadegan R.M., Irsen S, Famulok M. (2018). Supramolecular aptamer nano-constructs for receptor-mediated targeting and light triggered release of chemotherapeutics into cancer cells. Nat Commun 9, 535.
Yin, D.M., Hammler, D., Peter, M.F., Marx, A., Schmitz, A. & Hagelueken, G. (2018). Inhibitor-directed spin labelling - a high precision and minimally invasive technique to study the conformation of proteins in solution. Chem Eur J 24, 6665 - 6671.
Domenyuk, V., Zhong, Z., Stark, A., Xiao, N., O'Neill, H.A., Wei, X., Wang, J., Tinder, T.T., Tonapi, S., Duncan, J., Hornung, T., Hunter, A., Miglarese, M.R., Schorr, J., Halbert, D.D., Quackenbusch, J., Poste, G., Berry, D.A., Mayer, G., Famulok, M. & Spetzler, D. (2017) "Plasma exosome profiling of cancer patients by a next generation systems biology approach" Sci. Rep. 7, 42741
Valero, J., Lohmann, F., Keppner, D. & Famulok, M. (2016) "Single-Stranded Tile Stoppers for Interlocked DNA Architectures" ChemBioChem 17, 1146-1149
Weigandt, J., Chung, C.-L., Jester, S. S. & Famulok, M. (2016) "Daisy Chain Rotaxanes Made from Interlocked DNA Nanostructures" Angew. Chem. Int. Ed. Engl. 55, 5512-5516
Lentz, C.S., Sattler, J.M., Fendler, M., Gottwalt, S., Halls, V.S., Strassel, S., Arriens, S., Hannam, J.S., Specht, S., Famulok, M., Mueller, A.-K., Hoerauf, A. & Pfarr, K. (2015) "In vitro activity of wALADin benzimidazoles against different life cycle stages of plasmodium parasites" Antimicrob. Agents Chemother.59, 654 - 658
Lu, C.-H., Cecconello, A., Oi, X.-J., Wu, N., Jester, S.-S., Famulok, M., Matthies, M., Schmidt, T.-L. & Willner, I. (2015) "Switchable Reconfiguration of a seven-ring interlocked DNA catenane nanostructure" Nano Lett. 15, 7133 – 7137
Zhai, J., Zhang, L., Mojsilovic-Petrovic, J., Jian, X., Thomas, J., Homma, K., Schmitz, A., Famulok, M., Ichijo, H., Randazzo, P. A. & Kalb, R.G. (2015) "Inhibition of cytohesins protects against genetic models of motor neuron disease" J. Neurosci. 35, 9088 - 9105
Famulok, M. & Mayer, G. (2014) "Aptamers and SELEX in Chemistry & Biology" Chem. Biol. 21, 1055 - 1058
Jester, S.S. & Famulok, M. (2014) "Mechanically interlocked DNA nanostructures for functional devices" Acc. Chem. Res. 47, 1700 - 1709
Lentz, C.S., Halls, V.S., Hannam, J.S., Strassel, S., Lawrence, S.H., Jaffe, E.K., Famulok, M., Hoerauf, A. & Pfarr, K.M. (2014) "wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs" J. Med. Chem. 57, 2498 – 2510
Li, T., Lohmann, F. & Famulok, M. (2014) "Interlocked DNA nanostructures controlled by a reversible logic circuit" Nat. Commun. 5, 4940
Lohmann, F., Valero, J. & Famulok, M. (2014) "A novel family of structurally stable double stranded DNA catenanes" Chem. Commun. (Camb.) 50, 6091 - 6093
Lohmann, F., Weigandt, J., Valero, J. & Famulok, M. (2014) "Logic Gating by Macrocycle Displacement Using a Double-Stranded DNA 3 Rotaxane Shuttle" Angew. Chem. Int. Ed. Engl. 53, 10372 - 10376
Lu, C.H., Qi, X.J., Cecconello, A., Jester, S.S., Famulok, M. & Willner, I. (2014) "Switchable reconfiguration of an interlocked DNA olympiadane nanostructure" Angew. Chem. Int. Ed. Engl. 53, 7499 - 7503
Ackermann, D. & Famulok, M. (2013) "Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology" Nucleic Acids Res. 41, 4729 - 4739
Lentz, C.S., Stumpfe, D., Bajorath, J., Famulok, M., Hoerauf, A. & Pfarr, K. M (2015) "New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria" Bioorg. Med. Chem. Lett. 23, 5558 - 5562
Li, T. & Famulok, M. (2013) "I-motif-programmed functionalization of DNA nanocircles" J. Am. Chem. Soc. 135, 1593 - 1599
Niebel, B., Wosnitza, C.I. & Famulok, M. (2013) "RNA-aptamers that modulate the RhoGEF activity of Tiam1" Bioorg. Med. Chem. 21, 6239 - 6246
Albertoni, B., Hannam, J.S., Ackermann, D., Schmitz, A. & Famulok, M. (2012) "A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe" Chem. Commun. (Camb.) 48, 1272 - 1274
Bill, A., Schmitz, A., König, K., Heukamp, L.C., Hannam, J. S. & Famulok, M. (2012) "Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells" Plos One 7, e41179
Hons, M., Niebel, B., Karnowski, N., Weiche, B. & Famulok, M. (2012) "Pan-selective aptamers for the family of small GTPases" Chembiochem 13, 1433 - 1437
Li, J., Malaby, A.W., Famulok, M., Sabe, H., Lambright, D.G. & Hsu, V.W. (2012) "Grp1 plays a key role in linking insulin signaling to glut4 recycling" Dev. Cell 22, 1286 - 1298
Li, T., Ackermann, D., Hall, A.M. & Famulok, M. (2012) "Input-dependent induction of oligonucleotide structural motifs for performing molecular logic" J. Am. Chem. Soc. 134, 3508 - 3516
Lohmann, F., Ackermann, D. & Famulok, M. (2012) "Reversible light switch for macrocycle mobility in a DNA rotaxane" J. Am. Chem. Soc. 134, 11884 - 11887
Miao, B., Skidan, I., Yang, J., You, Z., Fu, X., Famulok, M., Schaffhausen, B., Torchilin, V., Yuan, J. & Degterev, A. (2012) "Inhibition of cell migration by PITENINs: the role of ARF6" Oncogene 31, 4317 - 4332
Rohrbach, F., Karadeniz, H., Erdem, A., Famulok, M. & Mayer, G. (2012) "Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes" Analytical biochemistry 421, 454 - 459
Vinkenborg, J.L., Mayer, G. & Famulok, M. (2012) "Aptamer-based affinity labeling of proteins" Angew. Chem. In.t Ed. Engl. 51, 9176 - 9180
Beyer, M., Thabet, Y., Müller, R.U., Sadlon, T., Classen, S., Lahl, K., Basu, S., Zhou, X., Bailey-Bucktrout, S.L., Krebs, W., Schönfeld, E.A., Böttcher, J., Golovina, T., Mayer, C.T., Hofmann, A., Sommer, D., Debey-Pascher, S., Endl, E., Limmer, A., Hippen, K.L., Blazar, B.R., Balderas, R., Quast, T., Waha, A., Mayer, G., Famulok, M., Knolle, P.A., Wickenhauser, C., Kolanus, W., Schermer, B., Bluestone, J.A., Barry, S.C., Sparwasser, T., Riley, J.L. & Schultze, J.L. (2011) "Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation" Nat. Immunol. 12, 898 - 907
Famulok, M. & Mayer, G. (2011) "Aptamer modules as sensors and detectors" Acc. Chem. Res. 44, 1349 - 1358
Niebel, B., Weiche, B., Mueller, A.L., Li, D.Y., Karnowski, N. & Famulok, M. (2011) "A luminescent oxygen channeling biosensor that measures small GTPase activation" Chem. Commun. 47, 7521 - 7523
Vinkenborg, J.L., Karnowski, N. & Famulok, M. (2011) "Aptamers for allosteric regulation" Nat. Chem. Biol. 7, 519 - 527
Ackermann, D., Schmidt, T.L., Hannam, J.S., Purohit, C.S., Heckel, A. & Famulok, M. (2010) "A double-stranded DNA rotaxane" Nat. Nanotechn. 5, 436 - 442
Lünse, C.E., Michlewski, G., Hopp, C.S., Rentmeister, A., Caceres, J.F., Famulok, M. & Mayer, G. (2010) "An aptamer targeting the apical-loop domain modulates pri-miRNA processing" Angew. Chem. Int. Ed. Engl. 49, 4674 - 4677
Mayer, G., Ahmed, M.S., Dolf, A., Endl, E., Knolle, P.A. & Famulok, M. (2010) "Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures" Nat. Protoc. 5, 1993 - 2004
Niebel, B., Lentz, C., Pofahl, M., Mayer, G., Hoerauf, A., Pfarr, K.M. & Famulok, M. (2010) "ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling" Chemistry 16, 11100 - 11107
Stumpfe, D., Bill, A., Novak, N., Loch, G., Blockus, H., Geppert, H., Becker, T., Schmitz, A., Hoch, M., Kolanus, W., Famulok, M. & Bajorath, J. (2010) "Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions" ACS Chem. Biol. 5, 839 - 849
Jones, C.A., Nishiya, N., London, N.R., Zhu, W., Sorensen, L.K., Chan, A., Lim, C.J., Chen, H., Zhang, Q., Schultz, P.G., Hayallah, A.M., Thomas, R.K., Famulok, M., Zhang, K., Ginsberg, H.H. & Li, D.Y. (2009) "Slit2-Robo4 signaling promotes vascular stability by blocking Arf6 activity" Nat. Cell Biol. 11, 1325-1331
Gronewold, T.M., Baumgartner, A., Hierer, J., Sierra, S., Blind, M., Schäfer, F., Blümer, J., Tillmann, T., Kiwitz, A., Kaiser, R., Zabe-Kühn, M., Quandt, E. & Famulok, M. (2009) "Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS)" J. Proteome Res. 8, 3568-3577
Beyer, M., Karbach, J., Mallmann, M.R., Zander, T., Eggle, D., Classen, S., Debey-Pascher, S., Famulok, M., Jäger, E. & Schultze, J.L. (2009) "Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy" Cancer Res. 69, 4346-4354
Erdem, A., Karadeniz, H., Mayer, G., Famulok, M. & Caliskan, A. (2009) "Electrochemical sensing of aptamer-protein interactions using magnetic particle assay and single-use sensor technology" Electroanalysis 21, 1278-1284
Famulok, M. (2009) "Exploring chemical space with aptamers" J. Med. Chem. 52, 6951-6957
Fusz, S., Srivatsan, S.G., Ackermann, D. & Famulok, M. (2008) "Photocleavable initiator nucleotide substrates for an aldolase ribozyme" J. Org. chem. 73, 5069-5077
Hafner, M., Vianini, E., Albertoni, B., Marchetti, L., Grüne, I., Gloeckner, C. & Famulok, M. (2008) "Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization" Nat. Prot. 3, 579-587
Heckel, A. & Famulok, M. (2008) "Building objects from nucleic acids for a nanometer world" Biochimie 90, 1096-1107
Mayer, G., Ackermann, D., Kuhn, N. & Famulok, M. (2008) "Construction of DNA architectures with RNA hairpins" Angew. Chem. Int. Ed. 47, 971-973
Raddatz, M.S., Dolf, A., Endl, E., Knolle, P., Famulok, M. & Mayer, G. (2008) "Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting" Angew. Chem. Int. Ed. 47, 5190-5193
Rasched, G., Ackermann, D., Schmidt, T.L., Broekmann, P., Heckel, A. & Famulok, M. (2008) "DNA minicircles with gaps for versatile functionalization" Angew. Chem. Int. Ed. 47, 967-970
Rentmeister, A., Mayer, G., Kuhn, N. & Famulok, M. (2008) "Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides" Biol. Chem. 389, 127-134