Schmitz, A., Weber, A., Mehtap, B., Breuers, S., Fieberg, V., Famulok, M., and Mayer, G. (2021). A SARS-CoV-2 spike binding DNA aptamer that inhibits pseudovirus infection in vitro by an RBD independent mechanism. Angew Chem Int Ed, online ahead of print. 
Valero, J. and Famulok, M. (2020). Regeneration of burnt bridges on a DNA catenane walker. Angew Chem Int Ed 59, 16366-16370.
Ma, Y., Centola, M., Keppner, D., and Famulok, M.
(2020).
Interlocked DNA nanojoints for reversible thermal sensing. Angew Chem
Int Ed 59, 12455-12459.
Hornung, T., O’Neill, H.A., Logie, S.C., Fowler, K.M.,
Duncan, J.E., Rosenow, M., Bondre, A.S., Tinder, T., Maher, V., Zarkovic, J.,
Zhong, Z., Richards, M.N., Wei, X., Miglarese, M.R., Mayer, G., Famulok, M., and Spetzler, D. (2020).
ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes. Nucleic Acids Res 48, 4013-4027.
Viegas, A., Yin, D.M., Borggraefe, J., Viennet, T.,
Falke, M., Schmitz, A., Famulok, M., and Etzkorn, M. (2020).
Molecular architecture of a network of potential intracellular EGFR modulators: ARNO, CaM, phospholipids, and the juxtamembrane segment. Structure 28, 54-62 e5.
Škugor, M., Valero, J., Murayama, K., Centola, M., Asanuma, H., and Famulok, M. (2019). Orthogonally photocontrolled non-autonomous DNA walker. Angew Chem Int Ed 58, 6948-6951.
Tonapi, S.S., Pannu, V., Duncan, J.E., Rosenow, M., Helmstetter, A., Magee, D., Zhang, Q., Tinder, T.T., Richards, M., Halbert D.D., Famulok, M., Spetzler, D., Miglarese, M.R., O'Neill, H.A., and Mayer, G. (2019). Translocation of a cell surface spliceosomal complex induces alternative splicing events and lymphoma cell necrosis. Cell Chem Biol 26, 756-764.e6.
Haydell, M.W., Centola, M., Adam, V., Valero, J., and Famulok M. (2018). Temporal and Reversible Control of a DNAzyme by Orthogonal Photoswitching. J Am Chem Soc 140, 16868-16872.
Kerzhner M., Matsuoka H., Wuebben C., Famulok M., and Schiemann O. (2018). High yield spin labeling of long RNAs for EPR spectroscopy. Biochemistry 57, 2923-2931.
Valero J., Pal N., Dhakal S., Walter N.G., and Famulok M. (2018). A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks. Nat Nanotechnol 13, 496-503.
Domenyuk V., Gatalica Z., Santhanam R., Wei X., Stark A., Kennedy P., Toussaint B., Levenberg S., Wang J., Xiao N., Greil R., Rinnerthaler G., Gampenrieder S.P., Heimberger A.B., Berry D.A., Barker A., Quackenbush J., Marshall J.L., Poste G., Vacirca J.L., Vidal G.A., Schwartzberg L.S., Halbert D.D., Voss A., Magee D., Miglarese M.R., Famulok M., Mayer G., and Spetzler D. (2018). Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes. Nat Commun 9, 1219.
Adam V., Prusty D.K., Centola M., Škugor M., Hannam J.S., Valero J., Klöckner B., and Famulok M. (2018). Expanding the toolbox of photoswitches for DNA nanotechnology using arylazopyrazoles. Chemistry 24, 1062-1066.
Prusty D.K., Adam V., Zadegan R.M., Irsen S, and Famulok M. (2018). Supramolecular aptamer nano-constructs for receptor-mediated targeting and light triggered release of chemotherapeutics into cancer cells. Nat Commun 9, 535.
Yin, D.M., Hammler, D., Peter, M.F., Marx, A., Schmitz, A., and Hagelueken, G. (2018). Inhibitor-directed spin labelling - a high precision and minimally invasive technique to study the conformation of proteins in solution. Chem Eur J 24, 6665 - 6671.
Domenyuk, V., Zhong, Z., Stark, A., Xiao, N., O'Neill, H.A., Wei, X., Wang, J., Tinder, T.T., Tonapi, S., Duncan, J., Hornung, T., Hunter, A., Miglarese, M.R., Schorr, J., Halbert, D.D., Quackenbusch, J., Poste, G., Berry, D.A., Mayer, G., Famulok, M., and Spetzler, D. (2017). Plasma exosome profiling of cancer patients by a next generation systems biology approach. Sci. Rep. 7, 42741.
Valero, J., Lohmann, F., Keppner, D., and Famulok, M. (2016). Single-stranded tile stoppers for interlocked DNA architectures. ChemBioChem 17, 1146-1149.
Weigandt, J., Chung, C.-L., Jester, S. S., and Famulok, M. (2016). Daisy chain rotaxanes made from interlocked DNA nanostructures. Angew. Chem. Int. Ed. Engl. 55, 5512-5516.
Lentz, C.S., Sattler, J.M., Fendler, M., Gottwalt, S., Halls, V.S., Strassel, S., Arriens, S., Hannam, J.S., Specht, S., Famulok, M., Mueller, A.-K., Hoerauf, A., and Pfarr, K. (2015). In vitro activity of wALADin benzimidazoles against different life cycle stages of plasmodium parasites. Antimicrob. Agents Chemother.59, 654 - 658.
Lu, C.-H., Cecconello, A., Oi, X.-J., Wu, N., Jester, S.-S., Famulok, M., Matthies, M., Schmidt, T.-L., and Willner, I. (2015). Switchable reconfiguration of a seven-ring interlocked DNA catenane nanostructure. Nano Lett. 15, 7133 – 7137.
Zhai, J., Zhang, L., Mojsilovic-Petrovic, J., Jian, X., Thomas, J., Homma, K., Schmitz, A., Famulok, M., Ichijo, H., Randazzo, P. A., and Kalb, R.G. (2015). Inhibition of cytohesins protects against genetic models of motor neuron disease. J. Neurosci. 35, 9088 - 9105.
Famulok, M. and Mayer, G. (2014). Aptamers and SELEX in chemistry & biology. Chem. Biol. 21, 1055 - 1058.
Jester, S.S. and Famulok, M. (2014). Mechanically interlocked DNA nanostructures for functional devices. Acc. Chem. Res. 47, 1700 - 1709.
Lentz, C.S., Halls, V.S., Hannam, J.S., Strassel, S., Lawrence, S.H., Jaffe, E.K., Famulok, M., Hoerauf, A., and Pfarr, K.M. (2014). wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J. Med. Chem. 57, 2498 - 2510.
Li, T., Lohmann, F. and Famulok, M. (2014). Interlocked DNA nanostructures controlled by a reversible logic circuit. Nat. Commun. 5, 4940.
Lohmann, F., Valero, J., and Famulok, M. (2014). A novel family of structurally stable double stranded DNA catenanes. Chem. Commun. (Camb.) 50, 6091 - 6093.
Lohmann, F., Weigandt, J., Valero, J., and Famulok, M. (2014). Logic gating by macrocycle displacement using a double-stranded DNA 3 rotaxane shuttle. Angew. Chem. Int. Ed. Engl. 53, 10372 - 10376.
Lu, C.H., Qi, X.J., Cecconello, A., Jester, S.S., Famulok, M., and Willner, I. (2014). Switchable reconfiguration of an interlocked DNA olympiadane nanostructure. Angew. Chem. Int. Ed. Engl. 53, 7499 - 7503.
Ackermann, D. and Famulok, M. (2013). Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology. Nucleic Acids Res. 41, 4729 - 4739.
Hussein, M., Bettio, M., Schmitz, A., Hannam, J.S., Theis, J., Mayer, G., Dosa, S., Gütschow, M., and Famulok, M. (2013). Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin. Angew. Chem. Int. Ed. Engl. 52, 9529 - 9533.
Lentz, C.S., Halls, V., Hannam, J.S., Niebel, B., Strübing, U., Mayer, G., Hoerauf, A., Famulok, M. & Pfarr, K.M. (2013) A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem. Biol. 20, 177 - 187.
Lentz, C.S., Stumpfe, D., Bajorath, J., Famulok, M., Hoerauf, A., and Pfarr, K. M (2015). New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria. Bioorg. Med. Chem. Lett. 23, 5558 - 5562.
Li, T. and Famulok, M. (2013). I-motif-programmed functionalization of DNA nanocircles. J. Am. Chem. Soc. 135, 1593 - 1599.
Niebel, B., Wosnitza, C.I., and Famulok, M. (2013). RNA-aptamers that modulate the RhoGEF activity of Tiam1. Bioorg. Med. Chem. 21, 6239 - 6246.
Ackermann, D., Jester, S.S., and Famulok, M. (2012). Design strategy for DNA rotaxanes with a mechanically reinforced PX100 axle. Angew. Chem. In.t Ed. Engl. 51, 6771 - 6775
Albertoni, B., Hannam, J.S., Ackermann, D., Schmitz, A., and Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chem. Commun. (Camb.) 48, 1272 - 1274.
Bill, A., Schmitz, A., König, K., Heukamp, L.C., Hannam, J. S., and Famulok, M. (2012). Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells. Plos One 7, e41179.
Hons, M., Niebel, B., Karnowski, N., Weiche, B., and Famulok, M. (2012). Pan-selective aptamers for the family of small GTPases. Chembiochem 13, 1433 - 1437.
Li, J., Malaby, A.W., Famulok, M., Sabe, H., Lambright, D.G., and Hsu, V.W. (2012). Grp1 plays a key role in linking insulin signaling to glut4 recycling. Dev. Cell 22, 1286 - 1298.
Li, T., Ackermann, D., Hall, A.M., and Famulok, M. (2012). Input-dependent induction of oligonucleotide structural motifs for performing molecular logic. J. Am. Chem. Soc. 134, 3508 - 3516.
Lohmann, F., Ackermann, D., and Famulok, M. (2012). Reversible light switch for macrocycle mobility in a DNA rotaxane. J. Am. Chem. Soc. 134, 11884 - 11887.
Miao, B., Skidan, I., Yang, J., You, Z., Fu, X., Famulok, M., Schaffhausen, B., Torchilin, V., Yuan, J., and Degterev, A. (2012). Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene 31, 4317 - 4332.
Rohrbach, F., Karadeniz, H., Erdem, A., Famulok, M., and Mayer, G. (2012). Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes. Analytical biochemistry 421, 454 - 459.
Vinkenborg, J.L., Mayer, G. & Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angew. Chem. In.t Ed. Engl. 51, 9176 - 9180.
Beyer, M., Thabet, Y., Müller, R.U., Sadlon, T., Classen, S., Lahl, K., Basu, S., Zhou, X., Bailey-Bucktrout, S.L., Krebs, W., Schönfeld, E.A., Böttcher, J., Golovina, T., Mayer, C.T., Hofmann, A., Sommer, D., Debey-Pascher, S., Endl, E., Limmer, A., Hippen, K.L., Blazar, B.R., Balderas, R., Quast, T., Waha, A., Mayer, G., Famulok, M., Knolle, P.A., Wickenhauser, C., Kolanus, W., Schermer, B., Bluestone, J.A., Barry, S.C., Sparwasser, T., Riley, J.L., and Schultze, J.L. (2011). Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat. Immunol. 12, 898 - 907.
Bill, A., Blockus, H., Stumpfe, D., Bajorath, J., Schmitz, A. & Famulok, M. (2011) "A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time" J. Am. Chem. Soc. 133, 8372 - 8379
Famulok, M. & Mayer, G. (2011) "Aptamer modules as sensors and detectors" Acc. Chem. Res. 44, 1349 - 1358
Niebel, B., Weiche, B., Mueller, A.L., Li, D.Y., Karnowski, N. & Famulok, M. (2011) "A luminescent oxygen channeling biosensor that measures small GTPase activation" Chem. Commun. 47, 7521 - 7523
Vinkenborg, J.L., Karnowski, N. & Famulok, M. (2011) "Aptamers for allosteric regulation" Nat. Chem. Biol. 7, 519 - 527
Ackermann, D., Rasched, G., Verma, S., Schmidt, T.L., Heckel, A. & Famulok, M. (2010) "Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates" Chem. Commun. (Camb.) 46, 4154 - 4156
Ackermann, D., Schmidt, T.L., Hannam, J.S., Purohit, C.S., Heckel, A. & Famulok, M. (2010) "A double-stranded DNA rotaxane" Nat. Nanotechn. 5, 436 - 442
Lünse, C.E., Michlewski, G., Hopp, C.S., Rentmeister, A., Caceres, J.F., Famulok, M. & Mayer, G. (2010) "An aptamer targeting the apical-loop domain modulates pri-miRNA processing" Angew. Chem. Int. Ed. Engl. 49, 4674 - 4677
Mayer, G., Ahmed, M.S., Dolf, A., Endl, E., Knolle, P.A. & Famulok, M. (2010) "Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures" Nat. Protoc. 5, 1993 - 2004
Niebel, B., Lentz, C., Pofahl, M., Mayer, G., Hoerauf, A., Pfarr, K.M. & Famulok, M. (2010) "ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling" Chemistry 16, 11100 - 11107
Stumpfe, D., Bill, A., Novak, N., Loch, G., Blockus, H., Geppert, H., Becker, T., Schmitz, A., Hoch, M., Kolanus, W., Famulok, M. & Bajorath, J. (2010) "Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions" ACS Chem. Biol. 5, 839 - 849
Klotz, L., Burgdorf, S., Dani, I., Saijo, K., Flossdorf, J., Hucke, S., Alferink, J., Nowak, N., Beyer, M., Mayer, G., Langhans, B., Klockgether, T., Waisman, A., Eberl, G., Schultze, J., Famulok, M., Kolanus, W., Glass, C., Kurts, C. & Knolle, P.A. (2009) "The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity" J. Exp. Med. 206, 2079-2089
Jones, C.A., Nishiya, N., London, N.R., Zhu, W., Sorensen, L.K., Chan, A., Lim, C.J., Chen, H., Zhang, Q., Schultz, P.G., Hayallah, A.M., Thomas, R.K., Famulok, M., Zhang, K., Ginsberg, H.H. & Li, D.Y. (2009) "Slit2-Robo4 signaling promotes vascular stability by blocking Arf6 activity" Nat. Cell Biol. 11, 1325-1331
Gronewold, T.M., Baumgartner, A., Hierer, J., Sierra, S., Blind, M., Schäfer, F., Blümer, J., Tillmann, T., Kiwitz, A., Kaiser, R., Zabe-Kühn, M., Quandt, E. & Famulok, M. (2009) "Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS)" J. Proteome Res. 8, 3568-3577
Beyer, M., Karbach, J., Mallmann, M.R., Zander, T., Eggle, D., Classen, S., Debey-Pascher, S., Famulok, M., Jäger, E. & Schultze, J.L. (2009) "Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy" Cancer Res. 69, 4346-4354
Erdem, A., Karadeniz, H., Mayer, G., Famulok, M. & Caliskan, A. (2009) "Electrochemical sensing of aptamer-protein interactions using magnetic particle assay and single-use sensor technology" Electroanalysis 21, 1278-1284
Famulok, M. (2009) "Exploring chemical space with aptamers" J. Med. Chem. 52, 6951-6957
Bi, X., Schmitz, A., Hayallah, A.M., Song, J.N. & Famulok, M. (2008) "Affinity-based labeling of cytohesins with a bifunctional SecinH3 photoaffinity probe" Angew. Chem. Int. Ed. 47, 9565-9568
Fusz, S., Srivatsan, S.G., Ackermann, D. & Famulok, M. (2008) "Photocleavable initiator nucleotide substrates for an aldolase ribozyme" J. Org. chem. 73, 5069-5077
Hafner, M., Vianini, E., Albertoni, B., Marchetti, L., Grüne, I., Gloeckner, C. & Famulok, M. (2008) "Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization" Nat. Prot. 3, 579-587
Heckel, A. & Famulok, M. (2008) "Building objects from nucleic acids for a nanometer world" Biochimie 90, 1096-1107
Mayer, G., Ackermann, D., Kuhn, N. & Famulok, M. (2008) "Construction of DNA architectures with RNA hairpins" Angew. Chem. Int. Ed. 47, 971-973
Raddatz, M.S., Dolf, A., Endl, E., Knolle, P., Famulok, M. & Mayer, G. (2008) "Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting" Angew. Chem. Int. Ed. 47, 5190-5193
Rasched, G., Ackermann, D., Schmidt, T.L., Broekmann, P., Heckel, A. & Famulok, M. (2008) "DNA minicircles with gaps for versatile functionalization" Angew. Chem. Int. Ed. 47, 967-970
Rentmeister, A., Mayer, G., Kuhn, N. & Famulok, M. (2008) "Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides" Biol. Chem. 389, 127-134